


Who we are
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We're a Bio-Tech startup, spun-out from Newcastle University in 2019
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Our ambition is to produce bio-equivalent tissues for clinical and cellular agriculture
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We apply novel bio-inspired manufacturing processes to generate complex structures

Who's who

Background
Our technology is built upon 20 years of basic research
Applying the hypothesis that a better understanding of biology will lead to improved approaches to tissue engineering we have developed a powerful new process we call TISSUE TEMPLATING
Tissue templating is an in-house engineering platform that takes a bio-inspired, bottom-up approach to tissue engineering to create STRUCTURED, FUNCTIONAL and SCALABLE tissues
Our products


Summary
Structured
Our tissue templating approach to engineering tissues is cell based. Highly organised structures with an accurate nano-scale through to macro-scale ensue.
Functional
Engineered tissue with appropriate hirearchical ECM arrangement produces unrilvaled performance and functionality.
Scalable
Our production suits a traditional centralised manufacturing approach, in which 100's of tissue engineered products can be produced daily and without the use of animal components.

Technology built upon science
Assessment of corneal substrate biomechanics and its effect on epithelial stem cell maintenance and differentiation
RM Gouveia, G Lepert, S Gupta, RR Mohan, C Paterson, CJ Connon 2019
Nature communications 10 (1), 1-17
4D Corneal Tissue Engineering: Achieving Time‐Dependent Tissue Self‐Curvature through Localized Control of Cell Actuators
M Miotto, RM Gouveia, AM Ionescu, F Figueiredo, IW Hamley, CJ Connon 2019
Advanced Functional Materials 29 (8), 1807334
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Template curvature influences cell alignment to create improved human corneal tissue equivalents
RM Gouveia, E Koudouna, J Jester,
F Figueiredo, CJ Connon 2017
Advanced Biosystems 1 (12), 1700135